Capsazepine decrease the pressor response to stimuli other than transient receptor potential vanilloid‐1 agonists
نویسندگان
چکیده
منابع مشابه
Capsazepine, a Transient Receptor Potential Vanilloid Type 1 (TRPV1) Antagonist, Attenuates Antinociceptive Effect of CB1 Receptor agonist, WIN55,212-2, in the Rat Nucleus Cuneiformis
Introduction: Nucleus cuneiformis (NCF), as part of descending pain inhibitory system, cooperates with periaqueductal gray (PAG) and rostral ventromedial medulla (RVM) in supraspinal modulation of pain. Cannabinoids have analgesic effects in the PAG, RVM and NCF. The transient receptor potential vanilloid type 1(TRPV1) can be activated by anandamide and WIN55,212-2 as a cannabinoid receptor ago...
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The myocardial response to exercise is an adaptive mechanism that permits the heart to maintain cardiac output via improved cardiac function and development of hypertrophy. There are many overlapping mechanisms via which this occurs with calcium handling being a crucial component of this process. Our laboratory has previously found that the stretch sensitive TRPV2 channels are active regulators...
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متن کاملcapsazepine, a transient receptor potential vanilloid type 1 (trpv1) antagonist, attenuates antinociceptive effect of cb1 receptor agonist, win55,212-2, in the rat nucleus cuneiformis
introduction: nucleus cuneiformis (ncf), as part of descending pain inhibitory system, cooperates with periaqueductal gray (pag) and rostral ventromedial medulla (rvm) in supraspinal modulation of pain. cannabinoids have analgesic effects in the pag, rvm and ncf. the transient receptor potential vanilloid type 1(trpv1) can be activated by anandamide and win55,212-2 as a cannabinoid receptor ago...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.lb492